Preconception & 1st Trimester
90 + 90 days
20+ Essential Micronutrients Including Iron, Folate & Calcium
Scientifically formulated by experts, TRIMACARE® Advance is a patented formulation designed to meet the nutritional requirements of Indian pregnant women during each trimester. It is India’s only trimester-specific pregnancy supplement, based on the advanced Multi-Micronutrient (MMN) model, and includes key micronutrients like Iron, Folate, and Calcium (IFC). By prescribing TRIMACARE® Advance, healthcare professionals can replace traditional IFC prescriptions with a comprehensive solution that aligns with the latest global & local pregnancy guidelines, ensuring positive outcomes in pregnancy and beyond.
Preconception, IVF & 1st trimester of Pregnancy
2nd Trimester of Pregnancy
3rd Trimester of Pregnancy & Lactation
Better Pregnancy Outcome, Better Patient Compliance
Multi-Micronutrient supplementation (MMN) is aligned with the latest clinical guidelines of ICMR & WHO[1–3] ensuring enhanced maternal & fetal health.
Supports Fetal Brain& Cognitive Development
L-Methyl Folate, in synergy with an optimal dose of Vitamin B12, Vitamin D3, Zinc, Veg Omega-3 fatty acids (DHA & EPA) & Iodine, contributes to the development of the fetal brain & cognitive functions by supporting neural tube formation, neurogenesis and synaptic connectivity.
Supports Fetal Brain& Organ Maturation
Time-release Iron, combined with Vitamin C, optimizes maternal hemoglobin levels, ensuring sufficient placental oxygen delivery. Vitamin B12 facilitates DNA synthesis, while Vitamin D3 & Vitamin K2 supports fetal skeletal development. Magnesium, Trace Minerals, & DHA further enhance the maturation of vital fetal organs & reduce the risk of preterm delivery.
Supports Maternal Health& Postpartum Recovery
Vitamin B6, with anti-emetic properties, alleviates nausea & morning sickness. Chromium & Vitamin D3 regulate maternal insulin sensitivity, reducing the risk of gestational diabetes. Veg Omega-3 fatty acids & Magnesium lower the likelihood of hypertensive disorders such as pre-eclampsia.
Reference
[1] Indian J Med Res. 2024 Jun;159(6):547-556
[2] Matern Child Nutr. 2024 Oct 2:e13722.
[3] WHO antenatal care recommendations for a positive pregnancy experience - NCBI Bookshelf
Backed by Data, Backed by 1000+ Doctors
Prof. Alka Kriplani
M.D., FRCOG, FAMs, FICOG, FIMsA, FICMCH, FCLs Director & Head, Obst.-Gynae & ART Paras Hospitals,Gurugram Ex-Professor & Head, Obst.-Gynae. AIIMS, New Delhi Ex-Director in-charge WHO-CCR, HRRC & Family Planning
“MMN supplementation of pregnant women represents an effective approach to reduce both maternal and foetal adverse outcomes compared to iron-folic acid supplementation alone.”
Read moreProf. Alka Kriplani
M.D., FRCOG, FAMs, FICOG, FIMsA, FICMCH, FCLs Director & Head, Obst.-Gynae & ART Paras Hospitals,Gurugram Ex-Professor & Head, Obst.-Gynae. AIIMS, New Delhi Ex-Director in-charge WHO-CCR, HRRC & Family Planning
“MMN supplementation of pregnant women represents an effective approach to reduce both maternal and foetal adverse outcomes compared to iron-folic acid supplementation alone.”
Dr Sadhana Gupta
Co–Chair SAFOG NCD Committee NIGF, President – 2022–24 VICE PRESIDENT FOGSI 2016 ICOG Governing Council Member (2015–21) SENIOR OB Gyn JJ hospital Gorakhpur (India)
“Hippocrates says 2500 year ago – “Let Food be thy medicine and medicine be thy food”. Around 1/10ᵗʰ of world population is suffering from hidden hunger and 1/4ᵗʰ from evident nutritional deficiency.”
Read moreDr Sadhana Gupta
Co–Chair SAFOG NCD Committee NIGF, President – 2022–24 VICE PRESIDENT FOGSI 2016 ICOG Governing Council Member (2015–21) SENIOR OB Gyn JJ hospital Gorakhpur (India)
“Hippocrates says 2500 year ago – “Let Food be thy medicine and medicine be thy food”. Around 1/10ᵗʰ of world population is suffering from hidden hunger and 1/4ᵗʰ from evident nutritional deficiency.”
Dr. Fessy Louis T
Senior Consultant & Associate Professor, Dept. of Reproductive Medicine & Surgery, AIMS - AMRITA Institute of Medical Sciences, Kochi
“As mentioned by Prof. CN Purandare, the past president of FIGO and a respected gynaecologist and obstetrician with more than 45 years of experience”
Read moreDr. Fessy Louis T
Senior Consultant & Associate Professor, Dept. of Reproductive Medicine & Surgery, AIMS - AMRITA Institute of Medical Sciences, Kochi
“As mentioned by Prof. CN Purandare, the past president of FIGO and a respected gynaecologist and obstetrician with more than 45 years of experience”
Dr. M. Gouri Devi
MBBS, MD (Gynecology and Obstetrics) Immed. Past President, Indian Fertility Society Director, Ridge Fertility and IVF Group Director, Gouri Hospital
“Multi‐micronutrient (MMN) deficiencies often coexist among women of reproductive age in developing nations. Micronutrients exert beneficial effects on female fertility and play essential role in different stages of conception.”
Read moreDr. M. Gouri Devi
MBBS, MD (Gynecology and Obstetrics) Immed. Past President, Indian Fertility Society Director, Ridge Fertility and IVF Group Director, Gouri Hospital
“Multi‐micronutrient (MMN) deficiencies often coexist among women of reproductive age in developing nations. Micronutrients exert beneficial effects on female fertility and play essential role in different stages of conception.”
Dr. Renu Chawla
M.D., Sr. Consultant Gynaecologist, Kailash Deepak Hospital, Delhi
“We as gynaecologists are obsessed with haemoglobin before and during pregnancy. We commonly prescribe iron, folic acid & calcium supplements. But we should equally focus on correcting MMN deficiency in pregnancy.”
Read moreDr. Renu Chawla
M.D., Sr. Consultant Gynaecologist, Kailash Deepak Hospital, Delhi
“We as gynaecologists are obsessed with haemoglobin before and during pregnancy. We commonly prescribe iron, folic acid & calcium supplements. But we should equally focus on correcting MMN deficiency in pregnancy.”
Dr. Sharda Jain
MNAMS, FICOG, FIMSA, DHM, QM & AHO PGDMLS (Symbiosis) Director Lifecare Centre, Lifecare IVF
“We as gynaecologists are obsessed with haemoglobin before and during pregnancy. We commonly prescribe iron, folic acid & calcium supplements. But we should equally focus on correcting MMN deficiency in pregnancy.”
Read moreDr. Sharda Jain
MNAMS, FICOG, FIMSA, DHM, QM & AHO PGDMLS (Symbiosis) Director Lifecare Centre, Lifecare IVF
“We as gynaecologists are obsessed with haemoglobin before and during pregnancy. We commonly prescribe iron, folic acid & calcium supplements. But we should equally focus on correcting MMN deficiency in pregnancy.”
Prof. Alka Kriplani
M.D., FRCOG, FAMs, FICOG, FIMsA, FICMCH, FCLs Director & Head, Obst.-Gynae & ART Paras Hospitals,Gurugram Ex-Professor & Head, Obst.-Gynae. AIIMS, New Delhi Ex-Director in-charge WHO-CCR, HRRC & Family Planning
“MMN supplementation of pregnant women represents an effective approach to reduce both maternal and foetal adverse outcomes compared to iron-folic acid supplementation alone.”
Read more
Dr Sadhana Gupta
Co–Chair SAFOG NCD Committee NIGF, President – 2022–24 VICE PRESIDENT FOGSI 2016 ICOG Governing Council Member (2015–21) SENIOR OB Gyn JJ hospital Gorakhpur (India)
“Hippocrates says 2500 year ago – “Let Food be thy medicine and medicine be thy food”. Around 1/10ᵗʰ of world population is suffering from hidden hunger and 1/4ᵗʰ from evident nutritional deficiency.”
Read more
Dr. Fessy Louis T
Senior Consultant & Associate Professor, Dept. of Reproductive Medicine & Surgery, AIMS - AMRITA Institute of Medical Sciences, Kochi
“As mentioned by Prof. CN Purandare, the past president of FIGO and a respected gynaecologist and obstetrician with more than 45 years of experience”
Read moreWhat are the Important Micronutrients for healthy pregnancy?
Importance of Multi Micronutrients in Pregnancy
First 1000 Days Nutrition for Pregnant Women and Prenatal Vitamins
Message from the Chairperson of UCAN Programme: Bringing together Doctors, Researchers and Nutritionists to improve pregnancy outcomes
The Menace of Hidden Hunger
1 in 2 pregnant women in India suffer from hidden hunger
The diets of both urban & rural women in India are often carbohydrate-rich but lack essential micronutrients. Studies reveal that one in every two pregnant women has deficiencies in 7-8 key micronutrients.[5-71]These deficiencies contribute to approximately 60% of adverse pregnancy outcomes.
Estimated prevalence of micronutrient deficiencies in pregnant women.
Increased Risks Associated with Micronutrient Deficiency:
- Preterm delivery & low-birth weight.
- Neurological & cognitive deficits in the fetus.
- Congenital anomalies.
- Cardiovascular diseases & insulin resistance.
- Thyroid dysfunction.
- Postpartum depression.
Challenges in Maternal Health in India
Comparison of Adverse Pregnancy Outcomes:
India
Developed countries
India has significantly higher rates of adverse pregnancy outcomes, such as Preterm Delivery (PTD), Low Birth Weight (LBW), Intrauterine Growth Restriction (IUGR), Pre-Eclampsia (PE), & Gestational Diabetes Mellitus (GDM), compared to developed nations.
For over two decades, developed countries have been prescribing Multi-Micronutrient (MMN) supplementation along with fortified foods to pregnant women.[10-17] The data emphasize the urgent need for India to transition from the traditional Iron, Folate & Calcium (IFC) supplementation model to an advanced MMN-based approach for improving pregnancy outcomes.
Importance of the 'First 1000 Days'
The First 1000 Days—from conception to a child's second birthday—represent a critical window for establishing lifelong health. Adequate nutrition during this period supports fetal development, strengthens immunity, & enhances cognitive outcomes, significantly impacting future health & well-being.
The first 300 days (from conception to birth) are particularly pivotal. Gynecologists play a crucial role in shaping maternal & fetal health during this phase. By prescribing tailored Multi-Micronutrient (MMN) supplementation rich in Folate, Veg Omega-3 fatty acids, lodine, Vitamin D, Carotenoids & Antioxidants, healthcare professionals can significantly enhance pregnancy outcomes & provide the foundation for a healthy start to the next generation.
How MMN Supplementation Improves Pregnancy Outcomes
Fetal Benefits:
Reduced risk of preterm birth by 55%.
Decreased risk of low birth weight by 15%.
Improved body composition, growth, respiratory health, & cognitive outcomes.
Lower risk of non-communicable diseases in adulthood, such as diabetes & cardiovascular disorders.
Maternal Benefits:
Reduced risk of pre-eclampsia by 45%.
Lower risk of gestational diabetes, osteoporosis, & thyroid dysfunction.
Reduced incidence of maternal anemia compared to iron & folate supplementation alone.
Enhanced energy levels, improved immunity, & faster postpartum recovery.
Reference
[18] J Health Popul Nutr. 2013 Jun; 31(2): 139-149.
[19] International Journal of Contemporary Medical Research Vol 3 | Issue 8 | Aug 2016.
[20] International Journal of Obstetrics and Gynaecology
[21] J Family Med Prim Care. 2018 Mar-Apr; 7(2): 324–330.
The First 1000 Days begin with TRIMACARE® Advance
Patented formulation with 20+ essential micronutrients from preconception to lactation.
2nd Trimester
90 days
3rd Trimester & Lactation
90 + 180 days
Advantage of TRIMACARE® over IFC
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✖Nutritional Insufficiency
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✖Poor Compliance
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✖Low Absorption & GI Side Effects
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✖Limited Symptomatic Relief
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✖Non-Specific Formulation
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✔Comprehensive Nutritional Support
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✔Enhanced Compliance
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✔Superior Iron Absorption
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✔Enhanced Symptomatic Relief
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✔Pregnancy-Specific Formulation
TRIMACARE
Advance
1
For Preconception, IVF & 1st Trimester of Pregnancy
Dosage:1 tablet per day
Therapy Duration:
30 days
Key Benefits
L-Methylfolate & Plant-Based Omega-3 [DHA]:
Essential for fetal brain & spinal development.
Pyridoxine & Anti-Emetic Blend:
Effectively reduces nausea & morning sickness during early pregnancy.
Comprehensive Nutrient Support:
Includes Vitamin D, Vitamin B12, Iodine, Zinc, & more to support optimal maternal & fetal health.
Replace Folic Acid with MMN for Superior Outcomes in IVF Therapy. Research supports that replacing traditional folic acid with Multi-Micronutrient (MMN) supplementation leads to:
- ✔ Improved embryo quality.
- ✔ Higher success in first attempt to achieve pregnancy.
- ✔ Better fertilization & clinical pregnancy outcomes.
TRIMACARE®
Advance
2
For 2ⁿᵈ Trimester of Pregnancy
Dosage:Twice daily (BD) Morning: 1 tablet (Iron component)
Dosage:1 tablet (Calcium component)
Therapy Duration:
30 days
Key Benefits
Iron (Time-Release)
Enhances blood flow and energy levels while minimizing gastrointestinal side effects.
Vitamin C:
Promotes higher iron absorption & strengthens immunity.
Plant-Based Omega-3 (DHA):
Supports fetal brain development & vision.
Vitamin D:
Essential for the healthy development of kidneys, heart, & the nervous system. Also reduces the risk of gestational diabetes.
Calcium & Magnesium:
Strengthens maternal bones and teeth while supporting fetal skeletal growth.
Time-Release Iron Technology
The human body can absorb only 12–15 mg of iron at one time. TRIMACARE® Advance 2 uses time-release technology to ensure optimal iron absorption, releasing 60 mg of elemental iron in 4 phases over 8 hours.
Advantage
- ✔ Improved absorption efficiency.
- ✔ Reduced gastrointestinal side effects like bloating & constipation.
TRIMACARE
Advance
3
For 3rd Trimester of Pregnancy & Lactation
Dosage:Twice daily (BD) Morning: 1 tablet (Iron component)
Dosage:1 tablet (Calcium component)
Therapy Duration
30 days
Key Benefits
Iron (Time-Release):
Improves blood flow & maternal energy levels with minimized gastrointestinal side effects.
Vitamin C
Enhances iron absorption & boosts maternal immunity.
Plant-Based Omega-3 (DHA):
Supports fetal brain & eye development.
Calcium & Vitamin D:
Strengthen maternal bones & teeth while supporting fetal skeletal growth & heart function.
Magnesium:
Prevents muscle cramps, alleviates pain & reduces the risk of pre-eclampsia.
Vitamin K:
Plays a crucial role in labor by supporting coagulation & maternal tissue repair.
Constipation Management:
Relieves constipation with a scientifically formulated blend of dietary fibers, including:
- Hull Lignans
- Foeniculum Vulgare
- Senna Alexandrina
- Zingiber Officinale
- Cuminum Cyminum
Optimal Magnesium Dose (310 mg) reduces risk of:
- ✔ Leg cramps
- ✔ Pre-eclampsia (PE)
- ✔ Preterm delivery (PTD)
- ✔ Intrauterine growth restriction (IUGR)
Loved by Mothers
Shruti
“I delivered my baby girl at Cloud Nine hospital, Mumbai. I tried multiple brands of iron but they didn’t suit me. Thankfully my doctor switched to TRIMACARE® Advance which was very gentle on my stomach & easy to consume.”
Riti
“I delivered at Fortis La Femme, Delhi. During my 1st pregnancy I had faced many complications but the second time my doctor prescribed TRIMACARE® Advance. I had a smooth experience & delivered a very healthy, full-term baby.”
Vartika
“I am a working professional. I delivered a baby boy at Apollo Cradle Hospital, Noida. Thanks to TRIMACARE® Advance, I didn’t have symptoms like morning sickness, pains or low energy which I hear from friends. I worked till my 35th week of pregnancy & resumed office after 3 months of delivery!”
