Life-Long Health Begins
With Maternal Nutrition
Trimacare® is a multi-micronutrient supplement
(MMS) including iron, folate, calcium.
Scientifically formulated for each trimester of
pregnancy.
>50% of pregnant women walk
into clinics with depleted reserves of an
average of 7–8 micronutrients
Pregnancy in India begins from a position of nutritional deficit.
Pregnant Women
are Anaemic
Births in India
are Preterm
Births in India are
Low Birth Weight
These figures are not driven by iron deficiency alone. Pregnant Indian women routinely present with simultaneous deficiencies of folate, vitamin B12, vitamin D, iodine, zinc, choline, and other essential micronutrients — a constellation termed hidden hunger.
An iron-folic acid regimen addresses two of those deficiencies. The remaining five or more go unaddressed. IFA is the foundation - but it was never designed for a deficiency landscape this broad
60% adverse pregnancy outcomes
linked to hidden hunger.
IFC covers 3. She needs 20+.
Three Pillars of Lifelong Health
Three converging frameworks establish maternal nutrition as a primary determinant of long-term offspring health.
1. Developmental Origins of Health and Disease (DOHaD)
"The DOHaD framework, established through decades of cohort and mechanistic research, has reframed maternal nutrition from a peripartum concern to a public-health lever that shapes a generation. Indian cohort data, most notably from the Pune Maternal Nutrition Study, confirm DOHaD effects in South Asian populations and document the distinctive thin-fat phenotype of Indian neonates - low overall body weight with relatively high fat mass, predisposing to lifelong metabolic risk."
Foundation of Developmental Origins of Health & Disease (DOHaD)
Maternal
Nutrition
Micronutrient status
shapes the intrauterine
environment.
Epigenetic
Programming
DNA methylation &
heritable gene
regulation
Fetal
Development
Organ architecture,
CNS, metabolic
pathways, immunity
Lifelong
Health
NCD risk, cognitive
capacity, metabolic
resilience
2. Epigenetics
The first human evidence came from the Dutch Hunger Winter cohort, where periconceptional famine exposure was associated with persistent DNA methylation differences six decades later. In the Indian context, the Pune Maternal Nutrition Study demonstrated that the imbalance between maternal vitamin B12 and folate during pregnancy is associated with offspring insulin resistance - linking one-carbon metabolism directly to long-term metabolic phenotype. A systematic review specific to Indian populations recommends policy expansion beyond iron-folic acid alone, citing the consistent association of low maternal B12 with adverse birth outcomes.
One-Carbon Metabolism Pathway
Adequate nutrition
MethylationProper gene regulation
DevelopmentOptimal organ function
Deficient nutrition
Folate/B12Insufficient substrates
TrajectoryLifelong NCD risk
3. The intergenerational cycle of malnutrition
If that child is female, she enters her own pregnancy already deficient. Recent analyses of Indian populations explicitly trace the micronutrient pathway through this cycle - maternal anaemia and chronic micronutrient shortages are associated with the thin-fat phenotype in newborns, perpetuating the intergenerational transmission of metabolic risk. The Lancet Maternal and Child Nutrition Series has documented that the effects of under-nutrition span at least three generations. The clinical implication is that intervention in this generation is intervention in the next.
The Intergenerational cycle of malnutrition
Infant Stunting, impaired cognition
Maternal nutrition is the single most modifiable factor influencing pregnancy outcomes & the lifelong health of the offspring.
”IFA alone is insufficient
Iron–folic acid (IFA) supplementation has been the cornerstone of antenatal nutrition programs in India since 1973. However, despite over five decades of implementation, anaemia continues to affect more than 50% of pregnant women.
This persistent burden highlights a critical gap: IFA addresses only two micronutrients in a clinical setting where deficiencies often span 7 or more essential micronutrients. It’s time to move beyond a limited approach and embrace comprehensive, multi-micronutrient supplementation for better maternal and fetal outcome.
Comparison of adverse pregnancy outcomes:
Countries
Yesterday
Today’s standard
IFA
Iron + Folic Acid
MMS
Multi-micronutrient Supplement
MMS improves pregnancy outcomes
Fetal benefits:
- Reduced risk of preterm birth by 55%.
- Decreased risk of low birth weight by 15%.
- Improved body composition, growth, respiratory health, & cognitive outcomes.
- Lower risk of non-communicable diseases in adulthood, such as diabetes and cardiovascular disorders.
Maternal benefits:
- Reduced risk of pre-eclampsia by 45%.
- Lower risk of gestational diabetes, osteoporosis, & thyroid dysfunction.
- Reduced incidence of maternal anemia compared to iron & folate supplementation alone.
- Enhanced energy levels, improved immunity, & faster postpartum recovery.
Antenatal multiple micronutrient supplements that include iron and folic acid are recommended in the context of rigorous research, in pregnant populations with documented micronutrient deficiencies.
” – World Health Organization Antenatal Care guideline (2016, updated 2020)
Why guidelines are
moving beyond IFA alone
- IFA fixes hemoglobin alone. Not outcomes.
- Anemia is multifactorial. B12, folate, copper, zinc — not iron alone.
- Multi-micronutrient deficiency is the norm in Indian pregnancy.
- Placental function needs more than iron. Iodine, choline, DHA carry their own load.
- Evidence favours MMS over IFA. Across birth weight, anemia, and neurodevelopment.
Trimacare® Patented Pregnancy Supplement
20+ Multi-micronutrient Supplement (MMS), including Iron, Folate & Calcium
Scientifically Formulated for each Trimester of Pregnancy
Cognitive Development
Organ Maturation
Postpartum Recovery
Scientifically formulated for each
trimester of pregnancy
Trimacare® 1
IVF & 1st Trimester 30
Tablets 1 Tablets
per day
Reduces
Morning sickness
Ginger + B6 anti-emetic blend
Supports
Neural tube formation
5-MTHF + Choline methyl-donor support
Reduces
Pregnancy fatigue
B-complex + Iodine energy metabolism
4th Generation Bioactive Folate (6S)-5-MTHF): 570 mcg | Choline: 100 mg | Veg Omega 3 (EPA:DHA 2:3): 100 mg | Anti emetic botanical blend: 200 mcg | Iodine: 200 mcg | Vitamin D: 600 IU | Vit B12: 2.45 mcg
Replace Folic Acid with Trimacare® 1
for Superior Outcomes in IVF Therapy.
- Improved embryo quality.
- Higher success rates in first attempt to achieve pregnancy.
- Better fertilization & clinical pregnancy outcomes.
Pregnancy (%)
in first attempt
Fertilization
rate (%)
Pregnancy
rate (%)
Trimacare® 2
Tablets BD
Reduces Anemia Risk
Iron + Vit C + Folate + Zinc + B12 for normal RBC formation
Reduces Brain Fog
Choline + DHA + Iodine Neurotransmission support
Support Bone & Muscle
B-complex + Calcium + Vit D + Magnesium + Iron Energy metabolism
Iron (ferrous fumarate): 27 mg | Vit C: 60 mg | Choline: 200 mg | Algal Omega 3 (EPA+DHA; 2:3): 200 mg | Vit B12: 2.45 mcg | Iodine: 200 mcg | Zinc: 12 mg | (6S)-5-MTHF: 570 mcg (Dietary Folate) | Calcium: 500 mg | Vit D: 600 IU | Magnesium: 206 mg | B-complex & more
Trimacare® 3
and Lactation 60
Tablets BD
Relief from
Constipation
Bowel regulator
(Dietary fiber)
Reduces
Leg Cramps
Higher Mg + Calcium + Vit D for muscle function
Support
Postpartum recovery
Iron + Folate + B complex + Vit D + Calcium
Iron (ferrous fumarate): 27 mg | Vit C: 60 mg | Choline: 200 mg | Algal Omega 3 (EPA+DHA; 2:3): 200 mg | Vit B12: 2.45 mcg | Iodine: 200 mcg | Zinc: 12 mg | (6S)-5-MTHF: 570 mcg (Dietary Folate) | Calcium: 500 mg | Vit D: 600 IU | Higher Magnesium: 310 mg | Bowel regulator (Dietary Fiber): 125 mg | B-complex & more
Superior patient compliance
of patients prefer a single pill vs
multiple pills
of patients reported better tolerability
as compared to iron tablets
of patients reported fewer pregnancy
symptoms like morning sickness,
constipation & fatigue
IFC
Trimacare®
- Nutritional Insufficiency
- Poor Compliance
- Low Absorption & GI Side Effects
- Limited Symptomatic Relief
- Non-SpecificFormulation
- Comprehensive Nutritional Support
- Enhanced Compliance
- Superior Absorption
- Enhanced Symptomatic Relief
- Pregnancy-Specific Formulation
What leading Ob-Gyns say about MMS
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FAQ — Answers from practising specialists.
How is Trimacare different from IFA + Calcium?
FOGSI's 2024 GCPR establishes the current Indian standard of care: iron 60–100 mg + folic acid 400 mcg daily plus calcium 1.5 g daily. This is the evidence-aligned foundation of antenatal supplementation in India. Indian pregnant women, however, present with documented simultaneous deficiencies of vitamin B12, vitamin D, iodine, zinc, choline, magnesium, and omega-3 — none of which an IFA + calcium regimen addresses.
Trimacare is a multiple micronutrient supplement (MMS) that provides over 20 nutrients in a trimester-specific, patented formulation. Cochrane systematic review (2019) and the New York Academy of Sciences expert review (2019) found that MMS reduces the risk of low birth weight, small-for-gestational-age, and stillbirth compared with IFA alone in low- and middle-income countries.
Why Quatrefolic® rather than folic acid?
Quatrefolic® is a biologically active folate form that supports folate availability without depending on the same conversion pathway required by folic acid.
Why does Trimacare include choline?
Choline supports fetal brain development, methylation pathways, and maternal nutritional needs during pregnancy.
Why ergocalciferol (D2) rather than cholecalciferol (D3)?
The formulation uses vitamin D support as part of a broader trimester-specific micronutrient profile.
What is the evidence base for MMS in pregnancy?
MMS has been studied across pregnancy outcomes including low birth weight, small-for-gestational-age births, stillbirth, and maternal nutritional status.
When should Trimacare be started, and for how long?
Trimacare is designed trimester-wise, beginning from preconception or early pregnancy and continuing through pregnancy as advised by the healthcare professional.
Rx Trimacare®
from the first antenatal visit
Improved Birth Outcomes.
Superior Patient Compliance.